CORDIS Project
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This project investigates the role of specific immune cells, dendritic cells and macrophages, in the lungs to understand how they balance tolerance to harmless substances and responses to pathogens. By developing innovative research tools, it aims to clarify the function of alveolar macrophages in regulating immune res…
The lung is a fascinating tissue at the level of immune regulation.
As barrier to the outside world it is in constant contact with innocuous environmental antigens, but is also the entrance site for many pathogens.
Importantly, loss of immune tolerance against environmental antigens, including pollen and house-dust-mite antigens, can cause severe allergic asthma.
Dendritic cells (DCs) and Macrophages (MFs) play an essential role in regulation of immune responses.
Thus lung DCs and lung MFs appea…
UNIVERSITEIT GENT
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