CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project focuses on enhancing cancer treatment through engineered T-cells that express specific receptors targeting tumors. It aims to determine the optimal affinity of these receptors for effective immune responses against tumors, particularly in melanoma patients.
Adoptive cell transfer of tumor-reactive lymphocytes has been shown to mediate the regression of large solid tumors in cancer patients.
To overcome the need to isolate and expand tumor-reactive lymphocytes that pre-exist in the patient, it is possible to engineer cells to express a tumor-specific T-cell receptor - TCR, thus reprogramming their specificity.
This pioneering therapeutic approach has been demonstrated to cause cancer regression in terminal melanoma patients that were refractory to p…
BAR ILAN UNIVERSITY
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
