CORDIS Project
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This project studies the maturation of viruses, specifically the HK97 bacteriophage, to understand the structural changes that occur during their development. By using advanced imaging techniques, the research aims to reveal the mechanisms behind viral assembly and maturation.
Virus maturation is virtually universal and allows the transition from an initially assembled non-infectious and fragile particle to a robust infectious virion.
Siphophage HK97 is an accessible model system, to study assembly and maturation, for which intermediates can be isolated and myriad structural, biophysical and biochemical data are available.
The capsid protein fold similarity between HK97, all other dsDNA bacteriophages and some animal viruses suggests that they share common maturation…
INSTITUT PASTEUR
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France, Marseille
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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