CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the structural mechanisms controlling the membrane attack complex of the immune system. It aims to understand how this complex operates and is regulated, which could inform new therapeutic strategies.
Structural basis of controlling the membrane attack complexComplement is a fundamental component of the human immune system; central to the battle between hosts and pathogens.
The membrane attack complex (MAC) is the direct killing arm of complement that acts by forming large pores in target cell membranes.
Uncontrolled activation results in by-stander damage, which can have devastating consequences for host cells and impact inflammatory pathologies, thrombosis and cancer.
Understanding how MAC…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
Guests see up to 5 keywords.
