CORDIS Project
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This project explores the role of Small Ubiquitin-related Modifier (SUMO) proteins in cellular processes. It aims to clarify the mechanisms of SUMO modification and its impact on protein interactions, which could enhance understanding of various biological functions and disease mechanisms.
The Small Ubiquitin-related MOdifier (SUMO) belongs to a family of proteins that become covalently attached to other proteins as post-translational modifications.
Proteins that are modified by SUMO participate in diverse cellular processes, including transcriptional regulation, nuclear transport, maintenance of genome integrity, and signal transduction.
Conjugation (or modification) by SUMO is controlled by an enzyme pathway analogous to the ubiquitin pathway.
The functional consequences of SUMO…
UNIVERSITAT AUTONOMA DE BARCELONA
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