CORDIS Project
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This project investigates a new regulatory mechanism in Streptomyces bacteria to enhance the production of secondary metabolites. By manipulating genetic pathways, it aims to activate previously dormant biosynthetic routes, potentially leading to the discovery of new natural products.
The aim of the StrepCrypPath is to test the industrial potential of a new approach to enhance Streptomyces secondary metabolism, discovered in our ERC-StG Strp-differentiation (280304) project.
We discovered a pleiotropic regulator of differentiation and secondary metabolism in the S. coelicolor model strain.
The S. coelicolor strain lacking this regulator is the first Streptomyces reported to produce secondary metabolites during its whole developmental cycle, including germination, the exponent…
UNIVERSIDAD DE OVIEDO
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