CORDIS Project
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STOP-HF focuses on generating heart cells from patients with specific types of heart failure to understand early molecular changes. By creating three-dimensional cardiac tissues and analyzing genetic differences, the project aims to uncover mechanisms of heart failure triggered by pregnancy and certain chemotherapy dru…
The overarching objective of STOP-HF is to generate human induced pluripotent stem cells (hiPSC) derived cardiomyocytes from two specific forms of heart failure (HF) with a clear trigger to unravel common pathophysiological mechanisms involved in the early development of HF.
The project is focused on two specific forms of HF, both with a clear trigger: pregnancy and anthracyclines.
Better understanding of early molecular pathways leading to HF and knowledge about inter-individual susceptibility…
UNIVERSITAIR MEDISCH CENTRUM GRONINGEN
ACADEMISCH ZIEKENHUIS GRONINGEN
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