CORDIS Project
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This project focuses on developing new methods for stereocontrolled substitutions in organic chemistry, specifically using non-classical carbocations derived from cyclopropyl carbinols. The goal is to create general protocols for SN1 reactions that allow precise control over stereochemistry, which is crucial for synthe…
SN1 reactions represent a possibility for stereocontrolled substitutions on tertiary and quaternary carbons, however the realization of this transformations remains an open issue.
To tackle the challenge of realizing general protocols including a stereochemical information in SN1 reactions, an intriguing viewpoint involve the exploitation of non-classical carbocation (NCCs). NCCs intrinsically have a stereochemically robust nature since one face is shielded by their carbon skeleton, allowing an…
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD
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TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY
Israel, Haifa
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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