CORDIS Project
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This project investigates the role of human embryonic stem cells in promoting protein homeostasis to slow aging and reduce age-related diseases. By studying mechanisms in the model organism C. elegans, the research aims to understand how proteostasis affects stem cell function and aging.
By 2050, the global population over the age of 80 will triple.
Thus, research for improving the quality of life at older age can be of enormous benefit for our ever-aging society.
To address this challenge we propose an innovative approach based on a combination of stem cell research with genetic experiments in C. elegans.
Mechanisms that promote protein homeostasis (proteostasis) slow down aging and decrease the incidence of age-related diseases.
Since human embryonic stem cells (hESCs) replica…
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