CORDIS Project
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This project aims to improve stem cell therapy for heart repair after myocardial infarction by encapsulating bone marrow stem cells in bioengineered collagen-based microspheres. These microspheres provide support for cell survival, enhance targeting to damaged areas, and promote re-vascularization, ultimately aiming to…
Stem cell therapy is believed to be the most viable method for restoration of cardiac function after Myocardial Infarction (MI), the leading cause of death in Europe.
Despite numerous attempts at injecting stem cells into post-MI heart to affect regeneration, the consensus is that anoikis (cell death) induced by the lack of contact between the cells and the tissue scaffold during injection, the harsh environment at the injection site, and powerful myocardial contractions cause massive cell loss…
Linköping University
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