CORDIS Project
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This project explores the activation of meningeal stem cells in the neurovascular unit, focusing on their potential therapeutic role in neurological disorders. It aims to understand how metabolic factors regulate these cells and their interactions with other brain cells.
The neurovascular Unit (NVU) consists of cerebral endothelial cells that interact physically and chemically with pericytes, astrocytes and microglial cells connected through the interactions with the basal lamina creating a functional barrier that regulates the movements of molecules into and out of the brain In the last two decades, the brain vasculature has increasingly been shown to have a key role in brain development, homeostasis, and disease.
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