CORDIS Project
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This project investigates how nutrition influences the function of tissue-resident stem cells in the intestine, particularly focusing on the role of a protein called Periodic tryptophan protein 1 in regulating stem cell behavior and aging. Using the fruit fly model, it aims to enhance understanding of stem cell aging a…
Tissues of animals undergo constant renewal.
This is enabled by pools of tissue-resident stem cells that differentiate to replace aged cells and maintain homeostasis.
However, stem cell self-renewal and differentiation capacities gradually start to decline during aging, leading to compromised organ function.
Nutrition has a prominent effect on aging and the maintenance of stem cell function.
Therefore, investigating the mechanisms responsible for nutrient regulation of tissue stem cells is of di…
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