CORDIS Project
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This project explores how specific brain circuits control self-initiated actions, focusing on the connections between the substantia nigra reticulata and the parvocellular reticular formation in mice. It aims to understand the neural mechanisms behind forelimb movements.
Behavior arises through the combination of movements within distributed circuits.
Most work in the past focused on high motor centers and executive circuits in the spinal cord, but how these systems are linked in order to function is poorly understood.The substantia nigra reticulata (SNR), a basal ganglia output, sends projections to the brainstem.
Yet how the brainstem processes these inputs to control actions remains unknown.
The Arber lab discovered that the parvocellular reticular formation…
FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION
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