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The STARLIGHT project studies the electron dynamics in DNA nucleobases when exposed to UV light. It aims to understand how these dynamics can lead to mutations, using advanced techniques to observe these processes in real time.
One of the challenges facing science is to understand the chemical origin of DNA damage-induced mutations.
Upon exposure to UV light, DNA nucleobases become electronically excited.
This process potentially favors mutagenic miscoding of the DNA sequence.The main target of STARLIGHT is to study with unprecedented temporal resolution (few-femtoseconds/attoseconds) the electron dynamics occurring in UV photoexcited biomolecules. I will mainly consider aromatic complexes including DNA nucleobases (an…
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