CORDIS Project
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This project explores the interactions between Staphylococcus aureus and skin cells in the context of atopic dermatitis. It aims to uncover the molecular mechanisms that regulate inflammation caused by this bacterium, potentially leading to new treatments for skin infections.
The skin provides a physical and immunological barrier to external environment and its homeostasis depends on interactions between keratinocytes, peripheral nerves, immune cells and microbiota.
One of the bacteria that can colonise skin is Staphylococcus aureus and it can be part of healthy skin or pathogen causing skin infection.
Importantly, in atopic dermatitis patients, which suffer from impaired skin barrier and microbiota dysbiosis, S. aureus is associated with severity of flares and exace…
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