CORDIS Project
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This project investigates small non-coding RNAs and their interactions with Argonaute proteins to understand gene regulation. It focuses on the role of specific microRNAs in glioblastoma stem cells, aiming to uncover new therapeutic targets for cancer treatment.
Small non-coding RNAs including microRNAs (miRNAs), short interfering RNAs (siRNAs) or Piwi interacting RNAs (piRNAs) have been discovered recently and extensive research revealed that such RNAs function as key-regulators of gene expression.
Small non-coding RNAs cooperate with members of the Argonaute (Ago) protein family to regulate gene expression at the level of transcription, mRNA stability or translation.
While small RNAs serve as sequence-specific guides, Ago proteins constitute the media…
UNIVERSITAET REGENSBURG
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