CORDIS Project
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This project explores the use of squalene-based compounds for drug delivery, focusing on how these drugs interact with cell membranes at a molecular level. By enhancing the transport of these drugs into cells, the project aims to improve their effectiveness in treating cancer and neurodegenerative diseases.
Squalene is a natural lipid precursor, which plays a crucial role in the biosynthesis of sterols in the cells .
Squalene is 100% biocompatible, not toxic and is able to enter into the cells easily.
This makes it very promising for creating highly efficient drugs and drug delivery systems.
The so-called squalenoylation technology is based on fusing hydrophobic squalenic acidwith the molecules of water-soluble drugs.
Resulting conjugated molecules spontaneously self-assemble into nanoparticles, w…
UNIVERSITE DE FRANCHE-COMTE
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