CORDIS Project
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This project aims to develop innovative treatments for stroke by exploring preconditioning mechanisms that protect brain tissue from ischemia. It focuses on the role of sphingosine 1-phosphate and its synthesis in neurons as potential therapeutic targets.
According to the European Cardiovascular Disease Statistics 2012 edition, over a third of deaths from cardiovascular disease in the EU are from coronary heart disease and just over a quarter are from stroke.
But there is a lack of effective treatment for most stroke patients.
Despite an expanding understanding of the cellular and molecular mechanisms underlying ischemia/reperfusion injury, 1000+ experimental compounds have failed at some stage of development.
Thus, innovative therapeutic approac…
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK
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