CORDIS Project
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The project investigates osteoarthritis by utilizing spatial transcriptomics to analyze the molecular profiles of cartilage and bone tissues. It aims to identify the cellular mechanisms involved in the disease's progression, enhancing understanding of osteoarthritis and potentially informing future treatments.
Osteoarthritis (OA) is the most prevalent chronic musculoskeletal disorder causing pain, morbidity and disability, giving rise to enormous healthcare expenditures and loss of work.
The exact triggers and pathogenesis of OA are still poorly understood.
Currently, there are no measures to slow down the progression of OA.
Bulk tissue-based multi-omics and small-scale single cell RNA-seq studies focussing on chondrocytes and synoviocytes have identified novel cell clusters, supporting the hypothesis…
HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
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