CORDIS Project
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This project develops a method to create light-emitting rodents that can be used to study disease progression and treatment effects without the need for frequent animal culling. By targeting specific organs, this innovative approach allows for real-time monitoring of disease models.
For decades, researchers have used small mammals to study the underlying processes of human disease and potential therapies for such ailments.
Current strategies for measuring disease progression and/or drug effect usually involve groups of animals being killed at multiple time points for post-mortem tissue analysis.
Recently, transgenic strains of mice have been created in which light-emitting luciferase is produced when a disease-specific pathway is switched on or off.
High-sensitivity cameras…
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United Kingdom, London
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
ST GEORGE'S HOSPITAL MEDICAL SCHOOL
United Kingdom, London
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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