CORDIS Project
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This project aims to create controlled biomolecular gradients that can influence cellular behavior without disrupting cellular communication. By utilizing DNA nanotechnology, the research seeks to enhance understanding of cellular processes and improve applications in tissue engineering.
Concentration gradients of biomolecules are essential in important biological events such as morphogenesis, inflammation, wound healing and cancer.
As a consequence, devising methods to generate highly controlled biomolecular gradients for studying cellular behaviour is a major scientific endeavor.
However, state-of-the-art approaches based on microfluidics suppress cellular signalling by washing molecules away, limiting their biological significance.
To solve this issue, this proposal will deve…
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