CORDIS Project
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This project investigates how bacteria sense and respond to environmental changes through signaling networks, focusing on the role of cyclic di-guanosine-monophosphate (c-di-GMP) and (p)ppGpp. Using advanced proteomics techniques, it aims to map these signaling networks in Escherichia coli and Caulobacter crescentus to…
To survive in diverse niches, bacteria must adapt to changes in their local environment by sensing and responding to environmental cues.
External cues are transduced through complex signaling networks throughout a cell and drive diverse changes in cellular behavior.
In bacteria, cyclic di-guanosine-monophosphate (c-di-GMP) is a nucleotide-derived second messenger that mediates signal transduction of important biological processes for bacterial growth and survival e.g. motility, biofilm formation…
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