CORDIS Project
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This project aims to develop a unified platform that enhances single molecule fluorescence techniques for studying protein complexes. By integrating advanced protein modification and microfluidic technologies, it seeks to improve throughput and provide detailed insights into protein dynamics and interactions.
Fluorescence techniques provide powerful means to study single protein machineries.
Single molecule observation of Fluorescence Resonance Energy Transfer (FRET) has become an important tool for probing structure, distances, dynamics, physicochemical properties and size of purified (in vitro) protein complexes.
Super-resolution techniques provide complementary spatial information about proteins in live (in vivo) specimen.
Although these techniques have become very popular because of their high se…
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