CORDIS Project
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This research focuses on understanding the free energy landscape of large functional RNA molecules, such as riboswitches and ribozymes. By employing single molecule techniques, the project aims to characterize intermediate and misfolded states, shedding light on RNA folding mechanisms.
In the last decade the increasing ability in the manipulation of small systems has led to a flourishing of single molecule studies.
Optical tweezers and atomic force microscopes are proving extremely versatile tools and they are currently enabling us to access the inner functioning of biomolecules at an unprecedented level of detail.
In particular, in the vast scenario of emerging experimental applications made possible by these techniques, experiments of mechanical unfolding and refolding of pr…
UNIVERSITAT DE BARCELONA
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