CORDIS Project
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This project aims to develop a hybrid delivery system by integrating virus-like structures with polymersomes. It focuses on creating a biocompatible vehicle that can efficiently deliver drugs, proteins, and genes to target cells, particularly for cancer treatment, using a combination of chemical and physical mechanisms…
In this proposal, we intend to combine the advantages of virus and polymersome structural motifs into one integrated model as a promising strategy to construct hybrid structures that are efficient delivery vehicles.
First, folic acid-modified polyN-(2-hydroxypropyl)methacrylamide-poly(L-cysteine) conjugate (FA-PHPMA-b-PLC) will be synthesized.
The biocompatible PHPMA is used as the hydrophilic part, and PLC is chosen for its ability to aggregate in water (by either hydrogen or covalent bonding v…
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