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The SLYDIV project investigates the assembly of S-layer proteins in Bacillus anthracis, focusing on their role in cell division and peptidoglycan synthesis. By exploring molecular interactions and using advanced imaging techniques, the project aims to enhance understanding of bacterial cell envelope regulation and deve…
Many bacteria possess a paracrystaline protein coat named the S-layer. S-layers cover the entire cell surface and are involved in protection, virulence, cell-shape maintenance and communication.
Lattice integrity is essential for S-layer function, meaning that its assembly must be intimately coordinated with cell growth and division.
Some studies have reported that S-layer biogenesis co-localizes with peptidoglycan (PG) synthesis, however, the underlying molecular mechanisms remain unknown.
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