CORDIS Project
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This project investigates sulfobacins, compounds produced in the gut that may help treat inflammatory bowel disease. It aims to understand their effects on gut microbiota and the biosynthetic pathways involved in their degradation and production.
Sulfobacins are sulfonated lipids that are bacterially synthesized in the gut and modulate the immune system and dampen intestinal inflammation.
Therefore, they are considered as potential therapeutics for targeted microbiome-oriented interventions in the increasing number of cases of inflammatory bowel disease.
However, the effects of sulfobacins on the gut microbiota, the degradation processes, and the key enzymes of the microbial biosynthetic pathway are unknown.
The complex human gut microbi…
UNIVERSITAT WIEN
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