CORDIS Project
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This project investigates how pregnancy alters the immune landscape of human skin, focusing on the balance between tolerance of fetal antigens and immune protection. By employing advanced transcriptomic technologies, it aims to uncover the signaling pathways involved in these changes, with the goal of mitigating inflam…
A successful immune adaptation to pregnancy is essential to support mammalian reproductive fitness.
Pregnancy presents a immunological dilemma where the maternal immune system must tolerate fetal antigens while maintaining its main protective functions.
How the maternal immune system navigates these opposing demands and adapt to pregnancy remains largely unclear.
This question is of importance at barrier sites such as the skin that represents a primary portal of infection and inflammatory disord…
INSTITUT PASTEUR
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