CORDIS Project
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This project investigates the role of oligodendroglia in multiple sclerosis by analyzing genetic variants associated with the disease. Using advanced techniques, it aims to uncover how these variants affect cell function and myelination, potentially leading to new therapeutic strategies.
Multiple sclerosis (MS) is a neurological disease characterized by autoimmune attack targeting oligodendroglia (OLG) in the central nervous system (CNS), and in particular their myelin, which ensheaths neuronal axons.
Genome-wide association studies (GWAS) have led to the identification of hundreds of single-nucleotide polymorphisms (SNPs) and variants that are associated with MS risk.
Many of these are located near genes associated with immune cells, indicating a key role for these cells in MS.…
KAROLINSKA INSTITUTET
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