CORDIS Project
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This project focuses on studying the interactions between proteins and DNA at the single-molecule level using DNA origami technology. It aims to develop high-throughput assays for analyzing these interactions, which are crucial for understanding biological regulatory processes.
Adhesive interactions between macromolecules are ubiquitously found in biology.
Regulatory processes in biology depend on temporary physical inter-biomolecular interactions whose strengths are regulated by the internal state of the cell.
Obtaining quantitative insight the dynamic strength of interactions between biomolecules has remained a difficult task.
Single-molecule approaches can provide detailed insight into intra-molecular interactions in biomolecules.
Yet, protein-protein and protein-DN…
TECHNISCHE UNIVERSITAET MUENCHEN
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