CORDIS Project
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This project investigates the mechanisms behind coeliac disease and its association with invasive lymphomas. By analyzing the tumor microenvironment and cellular responses, the research aims to identify potential therapeutic targets to improve treatment strategies for affected patients.
Coeliac disease is a chronic autoimmune-like enteropathy induced by dietary gluten in 0.5-2% Europeans. A rare but specific complication is the onset of invasive enteropathy-associated lymphomas.
The host laboratory has demonstrated that in approximately 70% of CD patients, invasive lymphomas are preceded by a clonal low-grade intraepithelial lymphoproliferation, usually called type II refractory CD (RCDII).I intend to take advantage of my experience in cellular immunology and single-cell analys…
IMAGINE INSTITUT DES MALADIES GENETIQUES NECKER ENFANTS MALADES FONDATION
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