CORDIS Project
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This project investigates how sex hormones influence kidney stem cells, focusing on their role in kidney disorders and the differences between males and females. It aims to uncover mechanisms that could explain the higher incidence of kidney diseases in men and the protective effects observed in women during pregnancy.
Kidney disorders represent a major global health burden with a significant sexual dimorphism that is largely unexplained.
My group first identified the stem cells of the kidney (renal progenitors) and demonstrated their crucial role in kidney disease.
Here, I propose that sex hormones regulate number and function of renal progenitors to empower females to face the hemodynamic and metabolic challenges of pregnancy. I further propose that this process impacts on sexual dimorphisms in incidence and…
UNIVERSITA DEGLI STUDI DI FIRENZE
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Denmark, Aarhus C
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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