CORDIS Project
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This project focuses on inflammatory bowel disease (IBD) and the role of specific immune signaling pathways in gut immunity. It aims to uncover how certain proteins influence autophagy and immune responses, potentially leading to new therapeutic strategies for IBD.
Inflammatory bowel disease (IBD) is a complex chronic pathology in western societies.
There is an unmet need for new therapeutic strategies which can only be achieved through a better understanding of the molecular mechanisms of host immunity.
It is established that dysregulated host innate immune recognition either caused by genetic risk variants in pathogen recognition receptor (PRR) molecules or microbial factors is commonly associated with IBD. A unique PRR family member, Nucleotide oligomer…
QUEEN MARY UNIVERSITY OF LONDON
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