CORDIS Project
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This research investigates the cellular dynamics of ovarian cancer, focusing on the differentiation of cancer stem cells and their mature counterparts. By mapping signaling states, the study aims to identify potential therapeutic targets to combat treatment resistance in ovarian cancer.
Tumors are by definition both variable and highly adaptive, allowing them to grow beyond their original onset site and invade other organs, and in the process evading physiological intra and extracellular anti-tumor responses, and sometimes chemotherapy.
This study proposes that ovarian cancers, and the heterogeneous cells that compose them, can be defined as a cell population(s) with an immature surface and signaling phenotype (with attendant self-replicative capacities) as well as a population…
EUROPEAN MOLECULAR BIOLOGY LABORATORY
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