CORDIS Project
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This project investigates the role of the protein SHP2 in breast cancer progression and metastasis, particularly in aggressive subtypes. It aims to understand SHP2's nuclear functions and its interaction with nucleolin, potentially leading to new therapeutic strategies for breast cancer.
Breast cancer is the most frequently diagnosed cancer in women with ~1.1 million worldwide cases.
Despite intense study, in a significant fraction of women, tumor progression and disease relapse is inevitable underscoring a crucial gap in our understanding of these important hallmarks.
Currently, little is known about the biochemical networks controlling these processes.
The host lab has shown a fundamental role for the protein tyrosine phosphatase, SHP2, in tumor progression and metastasis in t…
FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION
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