CORDIS Project
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The SHIELD project investigates viral glycosylation and entry dynamics of various viruses, including Zika and Ebola, to develop therapeutic interventions. By utilizing advanced molecular simulations and microscopy, it aims to design inhibitors and explore vaccine development to enhance pandemic preparedness.
The SHIELD consortium targets two closely related steps in the viral replication cycle that are, as yet, difficult to study and to exploit for therapeutic interventions: 1) Virion glycosylation in the context of uptake, maturation and viral immunity. 2) Virion dynamics of entry into cells, where the plasticity of the involved proteins and their glycosylation status have key roles.
The viruses studied in SHIELD are from the genera of flavivirus (DENV, WNV, YFV, Zika), mammarenaviruses (LASV) and…
RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
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STICHTING RADBOUD UNIVERSITEIT
Netherlands, Nijmegen
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Portugal, Lisboa
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Sweden, Stockholm
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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