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The SHARP project explores a bacterial defense system against viruses, focusing on the Shango Anti-phage Remodeling Pathway. By studying its molecular mechanisms, the project aims to develop new biotechnological tools for manipulating nucleic acids, enhancing our understanding of bacterial stress responses.
The SHARP (Shango Anti-phage Remodeling Pathway) project aims to explore the molecular mechanism of Shango system, a widespread bacterial anti-phage defense module.
While the well-known CRISPR-Cas systems have revolutionized genome editing, bacterial defense strategies encompass over 130 distinct gene modules and present a treasure chest for novel biotechnologies.
To eliminate viral threats, these systems employ various mechanisms, either pre- or post-injection.
Shango consists of three core gen…
KOBENHAVNS UNIVERSITET
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Humboldt Universität zu Berlin
Germany, +4930209346295
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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