CORDIS Project
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This project aims to develop a novel technology for delivering therapeutic compounds across the blood-brain barrier using small hydrophobic proteins. It focuses on understanding transport mechanisms and assessing the efficacy of new therapeutic agents for neurological disorders.
Neurological disorders affect over 540 million individuals in Europe alone, yet effective treatments are limited, primarily due to the challenge of delivering therapeutic compounds across the blood-brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSFB).
This project aims to develop a novel, virus-inspired technology that utilizes small hydrophobic (SH) proteins, derived from the neurotropic mumps virus to shuttle CNS-active molecules across the BCSFB via the GPR125 receptor.
This…
KOBENHAVNS UNIVERSITET
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