CORDIS Project
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This project aims to develop new drug candidates for schistosomiasis by targeting specific enzymes involved in histone modification in the parasite Schistosoma mansoni. Through a combination of genetic and chemical approaches, the project seeks to identify and validate therapeutic targets and screen potential inhibitor…
We propose to develop novel drug leads for the therapy of the major human parasitic disease, schistosomiasis, using a holistic approach that will enable us to progress from the cloned target protein to the lead compound and from epigenetic inhibitors to crucial targets.
For this, we have chosen to target the histone modifying enzymes (HME); histone deacetylases (HDAC), histone acetyltransferases (HAT), histone methyltransferases (HMT) and histone demethylases (HDM) of Schistosoma mansoni.
In the…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
France, Illkirch Graffenstaden
Type: Research institute
Activity type: Research Organisations
SME: No
Germany, Halle
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Brazil, Rio De Janeiro
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Germany, Freiburg
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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