CORDIS Project
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This research explores the neural mechanisms regulating sleep and wakefulness, focusing on the role of specific neurons in the brain of larval zebrafish. By utilizing advanced imaging and optogenetic techniques, the project aims to clarify how these neurons influence sleep cycles and related behaviors.
Summary:
The appropriate regulation of sleep and wakefulness is a fundamental biological process that impacts human health, cognitive performance, and quality of life.
However, the neural mechanisms regulating sleep/wake behavior and its associated circuits in the brain are largely unknown.
Recent studies have illustrated the role of hypocretin/orexin (Hcrt) in sleep regulation, but the mechanisms that control the Hcrt system and subsequent changes in neural circuit function are still poorly d…
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