CORDIS Project
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This study explores how the striatum, a key component of the basal ganglia, processes sensory information. By examining neuronal integration of sensory inputs, the research aims to uncover the mechanisms underlying sensory-motor functions and potential dysfunctions in the brain.
Motor behaviour requires the meaningful integration of a multitude of sensory information.
The basal ganglia are essential for such sensory-motor processing and underlie motor planning, performance, and learning.
The striatum is the input layer of the basal ganglia, acting as a “hub” that receives synaptic inputs from different brain regions, interacting primarily with the GABAergic striatal microcircuit.
Sensory excitatory inputs to striatum arise from the thalamus and neocortex, targeting stri…
KAROLINSKA INSTITUTET
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