CORDIS Project
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This project explores how chromosomes separate during cell division through a newly identified mechanism called self-clearing. By investigating the structural changes in chromosomes, the research aims to enhance understanding of chromosome segregation, which is crucial for genetic stability and has implications for dis…
In this research program, we propose the new concept that sister chromatid separation in mitosis is completed as a result of the dynamic intrinsic structural changes of chromosomes, i.e. through cycles of regional chromosome stretching and recoiling, which we call the self-clearing mechanism of chromosomes.
By developing several novel methods, we will establish this new concept and demonstrate that the self-clearing of chromosomes is an essential mechanism allowing complete removal of sister chr…
UNIVERSITY OF DUNDEE
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United Kingdom, Brighton
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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