CORDIS Project
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This project aims to uncover the molecular mechanisms that control the transition of malaria parasites from asexual to sexual reproduction. By focusing on the regulation of gametocyte formation, it seeks to identify potential targets for new malaria treatments.
Malaria is one of the major threats for human health worldwide and caused by unicellular organisms of the Plasmodium genus.
Within their mosquito vector and human host malaria parasites replicate almost exclusively asexually.
In order to be transmitted to mosquitoes formerly asexual parasites instead develop into gametocytes, which are the only forms that can infect mosquitoes.
Understanding the switch of asexual to sexual replication could offer new routes towards therapeutic intervention in se…
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