CORDIS Project
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This project aims to characterize the Type IX Secretion System in bacteria, which is crucial for protein transport and pathogenicity. It employs advanced techniques to understand the molecular details of this transport pathway.
The recently-discovered Type IX Secretion System (T9SS) is a protein transport pathway that exports proteins across the outer membrane of Gram-negative of the phylum Bacteroidetes.
It is an essential pathogenicity determinant in severe periodontal disease and in the major bacterial diseases of farmed fish.
It is also required for the unique Bacteroidete gliding motility.
The components required to catalyse T9SS export are still not fully defined, but include at least 18 authenticated proteins. P…
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