CORDIS Project
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This project investigates the mechanisms of intestinal regeneration in patients with inflammatory bowel disease (IBD) using an innovative organoid system and genome-wide CRISPR/Cas9 screening. The aim is to identify new regulators of tissue repair and potential drug targets to improve recovery in IBD patients.
Around 3 million people in Europe are affected by inflammatory bowel disease (IBD), a devastating condition characterized by chronic inflammation of the digestive tract causing severe damage to the intestinal epithelium.
Current medication strategies aim to relieve symptoms by reducing the inflammatory burden without promoting epithelial repair to restore tissue integrity.
It is therefore of great importance to enhance the current understanding of intestinal regeneration and thus facilitate the…
KOBENHAVNS UNIVERSITET
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