CORDIS Project
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The project explores the mechanisms of immunological memory in T and natural killer cells, focusing on their stem cell-like properties. By employing innovative tracking technologies, it aims to understand how these cells respond to infections and their potential for therapeutic applications.
Almost two decades ago it was first proposed that immunological memory may depend on stem cell-like mechanisms, enabling individual antigen-specific T and B cells to generate progeny that contains short-lived effectors as well as long-lived memory cells.
To test this capacity, I have in the past developed a stringent set of single cell-based approaches, which allowed me to show that single CD8+ and CD4+ T central memory cells harbour the capacity to self-renew and generate a diverse offspring of…
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
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Germany, Muenchen
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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