CORDIS Project
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This project focuses on characterizing chromatin states and their role in cellular differentiation using advanced single-cell sequencing techniques. It aims to uncover the relationship between chromatin regulation and gene expression variability.
Chromatin regulators adjust genome functions by modifying chromatin states.
Comprehensive characterization of chromatin states, associations of chromatin regulators, and expression profiles is crucial for investigating: 1.Cellular differentiation triggers. 2.The nature of the underlying chromatin regulatory mechanisms. 3.The effect of cellular heterogeneity, and 4.
How chromatin affects mRNA expression.
Mapping chromatin states by sequencing immunoprecipitated chromatin (ChIP-seq) provides an ex…
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