CORDIS Project
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This project investigates the interaction between Staphylococcus aureus biofilms and the human immune system. By analyzing protein expression during different growth stages, it aims to identify immune evasion molecules that could serve as potential drug targets against antibiotic-resistant infections.
During my postdoc at a marine biotechnology lab in Newcastle I experienced that bacteria growing in shakeflasks in the lab and bacteria in natural biofilms behave very differently.
For instance, the global gene expression and production of secreted proteins is very different between these modes of growth. I would like to bring the knowledge and skills acquired there to a higher level by studying the interaction between a clinically relevant biofilm and host organism.
To achieve this, I will stud…
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
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