CORDIS Project
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This project aims to develop next-generation direct-acting antivirals for hepatitis B virus using novel spirocyclic compounds. The focus is on creating highly potent drugs that can effectively combat chronic hepatitis B infections, addressing a significant global health challenge.
This PoC project aims to advance the development of next-generation direct-acting antivirals (DAAs) against hepatitis B virus (HBV), namely capsid assembly modulators (CAMs) with a novel spirocyclic scaffold chemotype described in our proprietary patent (WO2021/160617).
The identification of next-generation spirocyclic CAMs (S-CAMs) during the funding period of ERC CoG 725038 (FATE) represents a potentially important step towards the cure of chronic HBV infection, one of the major uncontrolled m…
OSPEDALE SAN RAFFAELE SRL
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