CORDIS Project
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This project focuses on developing a cancer therapy that enhances the body's natural tumor-suppressing microRNAs to combat hepatocellular carcinoma. It aims to identify and elevate these microRNAs to inhibit tumor growth and improve treatment outcomes.
The challenge for cancer therapy involves hampering the mechanisms by which the normal gene expression machinery is taken over to allow the aberrant appearance of cancer driving genes. I propose exploiting the therapeutic potential of a special class of tumor microRNAs (miRs) that function as natural post-transcriptional tumor suppressive regulators of many genes in key pathways.
These anti-cancer effectors represent an inherent organismal property that I propose to augment and thereby translate…
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